Role of non-coding RNA in cardiac remodeling
نویسندگان
چکیده
منابع مشابه
P87: The Role of the Long Non-Coding RNA Sequences (LncRNAs) in Neurological Disorders
Precise interpretation of the transcriptome sequences in the several species showed that the major part of genome has been transcribed; however, just a few amounts of the transcription sequences have open-reading frames which are conversed during the evolution. So, it is unlikely that many of the transcribed sequences code the proteins. Among the all human non-coding transcripts, at least 10000...
متن کاملLong Non-Coding RNAs in Cardiac Remodeling.
Cardiac remodeling occurs after stress to the heart, manifested as pathological processes, including hypertrophy and apoptosis of cardiomyocytes, dysfunction of vascular endothelial cells and vascular smooth muscle cells as well as differentiation and proliferation of fibroblasts, ultimately resulting in progression of cardiovascular diseases. Emerging evidence has revealed that long non-coding...
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متن کاملThe Role and Molecular Mechanism of Non-Coding RNAs in Pathological Cardiac Remodeling
Non-coding RNAs (ncRNAs) are a class of RNA molecules that do not encode proteins. Studies show that ncRNAs are not only involved in cell proliferation, apoptosis, differentiation, metabolism and other physiological processes, but also involved in the pathogenesis of diseases. Cardiac remodeling is the main pathological basis of a variety of cardiovascular diseases. Many studies have shown that...
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ژورنال
عنوان ژورنال: Non-coding RNA Investigation
سال: 2019
ISSN: 2522-6673
DOI: 10.21037/ncri.2019.03.02